Which item is generally not changed through the Properties option of a file?

Correct answer: Actual content of the file

The governing concept is the difference between file properties and file editing. Properties can display or change metadata and attributes such as the name, read-only status, and sometimes sharing permissions. They do not directly alter the words, pictures, or other data stored inside the file. Therefore, option D is correct; opening the file in its associated application is required to edit its actual content.