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If a positive extraction control fails what should be suspected?

Answer and explanation

Correct answer: A problem with the DNA extraction method or reagents

A positive extraction control contains a sample known to have DNA, so it should produce DNA after extraction. If this control fails, the likely problem is with the extraction procedure, such as an incorrect step, degraded reagents, or faulty reagents, rather than with the test sample. Option B is incorrect because DNA is already known to be present in the positive control. Exam tip: failure of a positive control indicates that the procedure should be checked before interpreting sample results.

Related tags

Positive Extraction ControlDna IsolationRecombinant Dna TechnologyQuality ControlExtraction ReagentsIsolation Of DnaProcesses Of Recombinant Dna TechnologyBiotechnology

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