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What problem can occur when a DNA pellet is over-dried?

Answer and explanation

Correct answer: DNA may become difficult to redissolve in buffer

An over-dried DNA pellet can become hard and compact, making it slow and difficult to redissolve in TE buffer or water. Ethanol is not formed from DNA, and cell lysis does not increase during pellet drying. Exam tip: After DNA precipitation, dry the pellet only enough to remove residual alcohol; do not let it become excessively hard.

Related tags

Dna IsolationDna PelletDna PrecipitationDna ResuspensionRecombinant Dna TechnologyIsolation Of DnaProcesses Of Recombinant Dna TechnologyBiotechnology

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