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What problem can occur if a DNA pellet is over-dried?

Answer and explanation

Correct answer: DNA may become difficult to dissolve in buffer

When a DNA pellet is over-dried, it can become hard and compact, making it slow or difficult to resuspend in TE buffer or water. DNA does not spontaneously convert into RNA, and drying does not increase protein content. Exam tip: Dry the pellet only enough to remove residual alcohol; avoid excessive drying before resuspension.

Related tags

Dna IsolationDna PelletResuspensionDna HandlingRecombinant Dna TechnologyIsolation Of DnaProcesses Of Recombinant Dna TechnologyBiotechnology

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