What is expected from a rare-cutter restriction enzyme?

Correct answer: Fewer cut sites and larger DNA fragments

A rare-cutter restriction enzyme usually recognizes a longer, specific recognition sequence. Such a long sequence occurs less frequently in DNA, so the enzyme cuts at fewer sites and produces larger DNA fragments. Many cut sites and small fragments are expected from a frequent-cutter enzyme. Exam tip: the longer the recognition sequence, the less often it is likely to occur.