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What is the simplest purpose of a DNA ladder?

Answer and explanation

Correct answer: To estimate the size of DNA fragments

A DNA ladder is a mixture of DNA fragments whose lengths are already known, commonly expressed in base pairs. It is loaded into a separate lane of an agarose gel and produces bands at reference positions. By comparing the migration distance of an unknown sample band with the corresponding ladder bands, a student can estimate the fragment’s approximate size. The estimate is not made by the ladder cutting DNA or producing enzymes; those are functions of other biological tools. A DNA ladder is also not a protein-staining reagent. Consequently, option A gives its simplest and correct purpose in gel electrophoresis.

Related tags

Dna LadderFragment SizeAgarose GelCutting Of DnaProcesses Of Recombinant Dna TechnologyBiotechnologyClass 11 Mcq

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