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What does modification show in restriction modification system?

Answer and explanation

Correct answer: host DNA methylation / Host DNA methylation

The direct answer is A: host DNA methylation. In a restriction–modification system, modification means that the host cell adds methyl groups to particular bases in its own DNA. This methyl marking protects host DNA from being cut by the matching restriction enzyme. The restriction part cuts unprotected foreign DNA, while the modification part protects self-DNA. Option A is correct because methylation is the protective modification. Option B, DNA gel run, only separates DNA fragments and does not protect DNA. Option C, protein digestion, concerns proteins rather than DNA methylation. Option D, ethanol precipitation, is a method for collecting or concentrating nucleic acids, not a protective marking system. Remember: modification marks self, restriction cuts foreign.

Related tags

ModificationMethylationRestriction Modification System

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