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If a recognition sequence is longer, how common is it generally in DNA?

Answer and explanation

Correct answer: Less common

The governing idea is the probability of finding a particular nucleotide sequence by chance. If bases are treated as approximately random, a specific sequence of length n has an expected frequency near 1 divided by 4 to the power n. Thus, a six-base recognition sequence has an approximate random frequency of 1/4⁶, whereas an eight-base sequence has 1/4⁸, which is much lower. Real genomes are not perfectly random, so the exact frequency varies with base composition and sequence bias, but the general trend remains: longer specific sites occur less often. Therefore option D is correct and such enzymes usually produce fewer cuts.

Related tags

Recognition SequenceSite FrequencyRestriction EnzymesPrinciples Of BiotechnologyBiotechnologyClass 11 Mcq

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