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Which type of DNA end has a single stranded overhang?

Answer and explanation

Correct answer: Sticky end

The governing concept is the structural difference between sticky and blunt DNA ends. A staggered restriction-enzyme cut leaves a short region of one strand unpaired at the end of the fragment. This single-stranded overhang is called a sticky or cohesive end because it can temporarily anneal with a complementary overhang. Such pairing helps align DNA fragments before ligase seals them. A blunt end, in contrast, is produced when both strands are cut at the same position and has no single-stranded projection. Closed end and mineral end are not standard DNA-end categories. Therefore option A is the only correct answer.

Related tags

Sticky EndSingle-Stranded OverhangBlunt EndRestriction EnzymesPrinciples Of BiotechnologyBiotechnologyClass 11 Mcq

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