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In which reaction does ligase need DNA ends to be close?

Answer and explanation

Correct answer: ligation reaction

The direct answer is A: the ligation reaction. Ligase works when two DNA ends are close enough and properly aligned. Step by step, compatible ends come together, ligase recognizes the nearby nick or break, and it forms a phosphodiester bond in the DNA backbone. This is why closeness is essential: the enzyme cannot join ends that are far apart. A is correct because ligation specifically means joining DNA fragments. B, photosynthesis, is the light-driven process by which plants make carbohydrates; it does not require ligase to join DNA ends. C, starch cooking, involves heat and changes in starch, not DNA joining. D, fat storage, concerns storing lipids in cells and has no role in ligase action. Do not confuse a reaction’s name with every biological process that may occur in a cell. Exam cue: “ligation” means “joining”; ligase joins adjacent DNA ends.

Related tags

Adjacent Dna EndsLigation ReactionDna Ligase

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