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Which option correctly links ligase and repair?

Answer and explanation

Correct answer: Sealing a nick in a DNA strand

DNA ligase seals a nick, a small break in the sugar-phosphate backbone of a DNA strand, by forming a phosphodiester bond. Thus, it restores strand continuity during DNA repair. Removing damaged bases is done by enzymes such as DNA glycosylases, not by ligase. Exam tip: Associate ligase with joining DNA fragments and sealing nicks.

Related tags

Dna LigaseDna RepairNick SealingPhosphodiester BondBiotechnology EnzymesLigase EnzymesPrinciples Of BiotechnologyBiotechnology

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