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Why is ligase called DNA glue?

Answer and explanation

Correct answer: It joins DNA fragments by forming phosphodiester bonds between them

DNA ligase seals nicks between adjacent DNA fragments or strands by forming phosphodiester bonds. This joining action is why it is called “DNA glue.” Cutting DNA at specific sites, as in option A, is the function of restriction enzymes, not ligase. Exam tip: remember ligase = joins; restriction enzyme = cuts.

Related tags

Dna LigasePhosphodiester BondRecombinant DnaRestriction EnzymesBiotechnology EnzymesLigase EnzymesPrinciples Of BiotechnologyBiotechnology

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