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Which statement is correct for ligase and DNA repair?

Answer and explanation

Correct answer: Ligase seals a nick in the sugar-phosphate backbone of DNA

During DNA repair, a nick may remain in the sugar-phosphate backbone of one DNA strand. DNA ligase forms a phosphodiester bond to seal this nick and restore strand continuity. Separating DNA strands is the function of helicase, not ligase. Exam tip: remember ligase as the enzyme that “joins” or “seals” DNA fragments and nicks.

Related tags

Dna LigaseDna RepairSugar Phosphate BackbonePhosphodiester BondReplication EnzymesLigase EnzymesPrinciples Of BiotechnologyBiotechnology

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