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Which option gives a correct biological role of ligase?

Answer and explanation

Correct answer: Joining fragments in DNA replication

The direct answer is A: ligase joins fragments during DNA replication. Replication produces the leading strand continuously but the lagging strand discontinuously, in short pieces called Okazaki fragments. After each fragment is made and its RNA primer is replaced with DNA, small breaks remain between neighbouring fragments. DNA ligase forms phosphodiester bonds and seals these breaks, producing one continuous strand. Option A is correct. Option B is wrong because making food in leaves is mainly photosynthesis, involving chlorophyll and light. Option C is wrong because calcium storage in bone involves cells and mineral tissue, not DNA ligase. Option D is wrong because oxygen transport in blood is mainly performed by haemoglobin in red blood cells. Ligase can also join DNA fragments in genetic engineering, but the replication example is a clear biological role. Memory cue: lagging strand leaves gaps; ligase links them.

Related tags

Biological RoleDna ReplicationLigase

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