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Which enzyme helps convert small DNA fragments into a continuous strand?

Answer and explanation

Correct answer: DNA ligase

DNA ligase joins breaks (nicks) in the sugar-phosphate backbone between short DNA fragments by forming phosphodiester bonds. Thus, it joins Okazaki fragments during replication to make a continuous strand. DNA polymerase adds new nucleotides, but DNA ligase performs the key function of sealing the nick between fragments. Exam tip: Choose DNA ligase when the question mentions joining fragments or sealing nicks.

Related tags

Dna LigaseDna ReplicationOkazaki FragmentsPhosphodiester BondBiotechnology EnzymesLigase EnzymesPrinciples Of BiotechnologyBiotechnology

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