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The source of T4 DNA ligase is associated with which organism?

Answer and explanation

Correct answer: T4 bacteriophage

T4 DNA ligase is the DNA-joining enzyme associated with bacteriophage T4, a virus that infects Escherichia coli. The enzyme catalyses the formation of phosphodiester bonds between adjacent DNA ends and is widely used in recombinant-DNA experiments. Its name identifies its biological source: T4 refers to the bacteriophage, while DNA ligase describes the enzyme activity. Therefore option A is correct. Human liver, plant roots and fungal caps are not the source indicated by the name and are not the standard biological source of T4 DNA ligase. The enzyme may be purified and used in laboratories, but its origin remains linked to phage T4.

Related tags

T4 BacteriophageT4 Dna LigaseEnzyme SourceLigase EnzymesPrinciples Of BiotechnologyBiotechnologyClass 11 Mcq

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