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How can an auxotrophic strain help in containment?

Answer and explanation

Correct answer: Survival outside the environment may decrease

An auxotrophic strain carries a metabolic defect that prevents it from making a nutrient or essential compound on its own. If that supplement is provided only in the laboratory, the strain may grow well under controlled conditions but have reduced survival after accidental release into an environment where the supplement is unavailable. Therefore, option A is correct and describes a potential biological-containment advantage. This is not an absolute guarantee, because environmental nutrients, compensatory mutations, or gene transfer can affect survival. Auxotrophy does not automatically make the host stronger, prevent DNA uptake, or remove a selectable marker.

Related tags

Auxotrophic StrainContainmentBiosafetyCompetent HostPrinciples Of BiotechnologyBiotechnologyClass 11 Mcq

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