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What does plasmid burden mean?

Answer and explanation

Correct answer: The extra resource load on a host cell caused by plasmid replication and maintenance

A plasmid requires host-cell resources such as energy, nucleotides and ribosomes for its replication, maintenance and gene expression. This extra metabolic cost is called plasmid burden, and it may reduce the host growth rate. Although a plasmid can carry an antibiotic-resistance gene, antibiotic inactivation is not the meaning of plasmid burden. Exam tip: link “burden” with extra demand on host resources.

Related tags

Plasmid BurdenCompetent HostHost CellMetabolic LoadPlasmid ReplicationBiotechnologyPrinciples Of BiotechnologyClass 11 Mcq

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