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Why is host compatibility important in a cloning vector?

Answer and explanation

Correct answer: The vector's ori can function with the host's replication machinery

The origin of replication (ori) of a cloning vector must be recognized by the host cell's replication machinery. Only then can the vector, along with its inserted DNA, replicate and produce many copies inside the host. Conversion of a vector into a protein is not its role; that idea is associated with expression of a gene. Exam tip: remember that ori enables replication, whereas a selectable marker helps identify transformed cells.

Related tags

Cloning VectorsHost CompatibilityOrigin Of ReplicationDna ReplicationBiotechnologyPrinciples Of BiotechnologyClass 11 Mcq

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