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Which vector is known for carrying large DNA inserts?

Answer and explanation

Correct answer: BAC

BAC stands for bacterial artificial chromosome. It is engineered from elements of bacterial plasmids and chromosomes so that it can maintain a comparatively large foreign DNA fragment in a bacterial host. BACs are useful in genomic libraries, physical mapping, and the study or sequencing of long genomic regions because they are generally maintained at low copy number, which can improve stability of large inserts. Option A is correct. Amylase and lipase are digestive enzymes, while insulin is a peptide hormone; none of these molecules is a DNA cloning vector. The defining clue is the ability to carry a large insert, not enzymatic or hormonal activity.

Related tags

BacLarge InsertCloning VectorCloning VectorsPrinciples Of BiotechnologyBiotechnologyClass 11 Mcq

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